Clone:
REAL1157
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
Myosin Heavy Chain (Skeletal Muscle), Myosin heavy chain 1, MyHC-2x, MyHC-IIx/d, MYH1

Specifications for Myosin-1 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL1157 is an antibody fragment derived from the full Myosin-1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1157 recognizes the human Myosin-1, also known as Myosin Heavy Chain, Skeletal Muscle. Myosins are a superfamily of genes, whose proteins are involded in muscle contraction and various motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility. Skeletal muscle myosin, the most conspicuous of the myosin superfamily, makes up part of the sarcomere and forms macromolecular filaments composed of multiple myosin subunits. Myosin-1 is specific for the myosin heavy chain in skeletal muscle and does not recognize human or animal cardiac or smooth muscle myosin.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Myosin Heavy Chain (Skeletal Muscle), Myosin heavy chain 1, MyHC-2x, MyHC-IIx/d, MYH1

Detailed product information

Technical specifications

CloneREAL1157
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenMyosin-1
Alternative names of antigenMyosin Heavy Chain (Skeletal Muscle), Myosin heavy chain 1, MyHC-2x, MyHC-IIx/d, MYH1
Distribution of antigenskeletal muscle

Resources for Myosin-1 Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for Myosin-1 Antibody, anti-human, REAdye_lease™

Publications

  1. Novakovic, V. A. et al. (2020) Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid. Blood 136(21): 2469-2472
  2. Deguchi, H. et al. (2021) Novel blood coagulation molecules: Skeletal muscle myosin and cardiac myosin. J. Thromb. Haemost. 1: 7-19

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