Clone:
M5/114.15.2
Type of antibody:
Primary antibodies
Isotype:
rat IgG2bκ
Applications:
FC, MICS, IF, IHC
Alternative names:
H2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1

Specifications for MHC Class II Antibody, anti-mouse

Overview

The Anti-MHC Class II antibody reacts with the MHC class II alloantigens I-Ab, I-Aq, I-Ad, I-Ed, and I-Ek that are expressed by most common inbred mouse strains, for example, C57BL/6, BALB/c, or 129/SvEv 1. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes/macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow.

Alternative names

H2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1

Detailed product information

Technical specifications

CloneM5/114.15.2
Clonalitymonoclonal
Isotyperat IgG2bκ
Isotype controlIsotype Control Antibody, rat IgG2b
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenMHC Class II
Alternative names of antigenH2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1
Molecular mass of antigen [kDa]27
Distribution of antigendendritic cells, monocytes, macrophages, epithelial cells, stem cells, cancer stem cells, hematopoietic stem and progenitor cells
Entrez Gene ID14961
RRIDAB_2802021, AB_2802055, AB_2811551, AB_2660055, AB_2660056, AB_2660063, AB_2660064, AB_2660065, AB_2660066, AB_2734108

References for MHC Class II Antibody, anti-mouse

Publications

  1. Bhattacharya, A. et al. (1981) A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J. Immunol. 127(6): 2488-2495

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