Clone:
REA1093
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
MLANA, MART1, Melan-A

Specifications for MART-1 Antibody, anti-human, REAfinity™

Overview

Clone REA1093 recognizes the human MART-1 protein, also known as Melan-A, which is an 18 kD transmembrane protein and expressed in cells of melanocytic lineage. MART-1 is expressed by a large proportion of melanomas and by melanoma cell lines. A fragment of the protein is bound by MHC class I complexes which present it to cytotoxic T cells of the immune system.
Additional Information: Clone REA1093 displays negligible binding to Fc receptors.

Alternative names

MLANA, MART1, Melan-A

Detailed product information

Technical specifications

CloneREA1093
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenMART-1
Alternative names of antigenMLANA, MART1, Melan-A
Distribution of antigenmelanoma
RRIDAB_2857437, AB_2857438, AB_2857436

References for MART-1 Antibody, anti-human, REAfinity™

Publications

  1. Rimoldi, D. et al. (2001) Subcellular localization of the melanoma-associated protein Melan-AMART-1 influences the processing of its HLA-A2-restricted epitope. J. Biol. Chem. 276(46): 43189-43196
  2. De Mazière, A. M. et al. (2002) The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins. Traffic 3(9): 678-693