REAlease® CD11b Complexes, human

CD11b Complexes
, human

Clone: REAL744 | Dilution: 1:50
Clone REAL744 is an antibody fragment derived from the full CD11b antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL744 recognizes the human CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

integrin αM, Mac-1 α, Integrin alpha-M, CR3A

Technical specifications

  • Antigen: CD11b
  • Clone: REAL744
  • Isotype control: REAL Control
  • Alternative names of antigen: integrin αM, Mac-1 α, Integrin alpha-M, CR3A
  • Distribution of antigen: myeloid cells, NK cells, microglia, brain, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
Product options: 1
for 100
EUR 216,00