CD8b.2 antibodies, mouse

CD8b.2 antibodies, mouse

Clone: REA865 | Dilution: 1:50
Clone REA865 recognizes the β chain of the mouse CD8 antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3.2 or Lyt-3.2). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8 αα homodimer or as a CD8 αβ heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8
+
lymphocyte subsets. The CD8 αβ heterodimer is expressed on cytotoxic T cells and thymocytes. CD8b functions as a co-receptor for the T cell receptor (TCR).
Additional information: Clone REA865 displays negligible binding to Fc receptors.

Alternative Names

Lyt-3.2, Ly-3.2

Technical specifications

  • Antigen: CD8b.2
  • Clone: REA865
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Lyt-3.2, Ly-3.2
  • Entrez Gene ID: 12526
  • Molecular mass of antigen [kDa]: 22
  • Distribution of antigen: T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected References

    1. Chang, H. C. et al. (2005) Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer. Immunity 23(6): 661-671
    2. Renard, V. et al. (1996) CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding. J. Exp. Med. 184(6): 2439-2444
    3. Gao, G. F. et al. (2000) Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol. Today 21(12): 630-636
Product options: 16
130-114-384

CD8b.2-FITC, mouse

30 µg in 200 µL (1)
EUR 40,00 
130-114-277

CD8b.2-FITC, mouse

150 µg in 1 mL (1)
EUR 120,00 
130-114-385

CD8b.2-PE, mouse

30 µg in 200 µL (1)
EUR 80,00 
130-114-278

CD8b.2-PE, mouse

150 µg in 1 mL (1)
EUR 230,00 
130-114-386

CD8b.2-APC, mouse

30 µg in 200 µL (1)
EUR 80,00 
130-114-279

CD8b.2-APC, mouse

150 µg in 1 mL (1)
EUR 230,00 
130-114-391

CD8b.2-VioBlue, mouse

30 µg in 200 µL (1)
EUR 95,00 
130-114-284

CD8b.2-VioBlue, mouse

150 µg in 1 mL (1)
EUR 275,00 
130-114-387

CD8b.2-PE-Vio770, mouse

30 µg in 200 µL (1)
EUR 100,00 
130-114-280

CD8b.2-PE-Vio770, mouse

150 µg in 1 mL (1)
EUR 295,00 
130-114-388

CD8b.2-APC-Vio770, mouse

30 µg in 200 µL (1)
EUR 100,00 
130-114-281

CD8b.2-APC-Vio770, mouse

150 µg in 1 mL (1)
EUR 295,00 
130-114-389

CD8b.2-PerCP-Vio700, mouse

30 µg in 200 µL (1)
EUR 100,00 
130-114-282

CD8b.2-PerCP-Vio700, mouse

150 µg in 1 mL (1)
EUR 295,00 
130-114-383

CD8b.2-Biotin, mouse

30 µg in 200 µL (1)
EUR 40,00 
130-114-276

CD8b.2-Biotin, mouse

150 µg in 1 mL (1)
EUR 120,00