CD79b antibodies, human

CD79b antibodies, human

Clone: REA120 | Dilution: 1:11
Clone REA120 detects the extracellular epitope of CD79b, the β chain of heterodimeric molecule CD79. CD79 is composed of an α chain (CD79a) and a β chain (CD79b) and is associated with surface immunoglobulins (Igs) to form the B cell receptor (BCR). CD79b is 37–39 kDa type I integral membrane protein and like CD79a contains an intracellular immunoreceptor tyrosine-based activation motif (ITAM). CD79a/CD79b heterodimer facilitates differentiation of pre–B cells from pro–B cells, surface expression of sIg, signal transduction following antigen recognition, and enodocytosis of recognised antigens. Patients with chronic lymphocytic leukemia (CLL) B cells lack a functional BCR which is often associated with mutations in CD79b coding region.
Additional information: Clone REA120 displays negligible binding to Fc receptors.

Alternative Names

AGM6, B29, Igb

Technical specifications

  • Antigen: CD79b
  • Clone: REA120
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: AGM6, B29, Igb
  • Entrez Gene ID: 974
  • Molecular mass of antigen [kDa]: 23
  • Cross-reactivity:
    chimpanzee (
    Pan troglodytes
    )
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, PerCP-Vio700, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD79b-PE, human

  • REA120
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-106
EUR 91,00 

CD79b-PE, human

  • REA120
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-104
EUR 236,00 

CD79b-APC, human

  • REA120
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-103
EUR 113,00 

CD79b-APC, human

  • REA120
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-101
EUR 255,00 

CD79b-PE-Vio770, human

  • REA120
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-170
EUR 113,00 

CD79b-PE-Vio770, human

  • REA120
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-168
EUR 278,00 

CD79b-PerCP-Vio700, human

  • REA120
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-173
EUR 101,00 

CD79b-PerCP-Vio700, human

  • REA120
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-171
EUR 300,00 

CD79b-Biotin, human

  • REA120
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-117
EUR 74,00 

CD79b-Biotin, human

  • REA120
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-137
EUR 236,00 

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