CD69 antibodies, human

CD69 antibodies, human

Clone: REA824 | Dilution: 1:50
Clone REA824 recognizes the human CD69 antigen, also known as activation inducer molecule (AIM). CD69 is involved in the early events of lymphocyte, monocyte, and platelet activation. Cross-linking of CD69 induces cytotoxic activity and costimulates cytokine production of activated NK cells and selected T cell clones. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. It is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4
+
T cells in germinal centers of normal lymph nodes.
Additional information: Clone REA824 displays negligible binding to Fc receptors.

Alternative names

AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, VEA

Technical specifications

  • Antigen: CD69
  • Clone: REA824
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, VEA
  • Entrez Gene ID: 969
  • Molecular mass of antigen [kDa]: 23
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    , baboon
  • Distribution of antigen: B cells, eosinophils, Langerhans cells, leukocytes, lymphocytes, neutrophils, NK cells, platelets, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Hamann, J. et al. (1993) Expression cloning of the early activation antigen CD69, a type II integral membrane protein with a C-type lectin domain. J. Immunol. 150(11): 4920-4927
    2. López-Cabrera, M. et al. (1993) Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors. J. Exp. Med. 178(2): 537-547
    3. Lin, G. X. et al. (2002) Cross-reactivity of CD antibodies in eight animal species. In: Leucocyte typing VII, Oxford University Press. : 519-524
Product options: 18
130-112-801

CD69-FITC, human

for 30
tests
(1)
EUR 70,00 
130-112-612

CD69-FITC, human

for 100
tests
(1)
EUR 175,00 
130-112-802

CD69-PE, human

for 30
tests
(1)
EUR 95,00 
130-112-613

CD69-PE, human

for 100
tests
(1)
EUR 235,00 
130-112-803

CD69-APC, human

for 30
tests
(1)
EUR 95,00 
130-112-614

CD69-APC, human

for 100
tests
(1)
EUR 235,00 
130-112-799

CD69-VioBlue, human

for 30
tests
(1)
EUR 115,00 
130-112-610

CD69-VioBlue, human

for 100
tests
(1)
EUR 275,00 
130-112-800

CD69-VioGreen, human

for 30
tests
(1)
EUR 115,00 
130-112-611

CD69-VioGreen, human

for 100
tests
(1)
EUR 275,00 
130-112-806

CD69-PE-Vio615, human

for 30
tests
(1)
EUR 120,00 
130-112-617

CD69-PE-Vio615, human

for 100
tests
(1)
EUR 290,00 
130-112-804

CD69-PE-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-112-615

CD69-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-112-805

CD69-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-112-616

CD69-APC-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-112-798

CD69-Biotin, human

for 30
tests
(1)
EUR 70,00 
130-112-609

CD69-Biotin, human

for 100
tests
(1)
EUR 175,00