CD54 (ICAM-1) antibodies, human

CD54 (ICAM-1) antibodies, human

Clone: REA266 | Dilution: 1:11
Clone REA266 recognizes human CD54, a 85–110 kDa type I transmembrane glycoprotein, which also known as intercellular adhesion molecule 1 (ICAM-1). CD54 is continuously present in low concentrations in the membranes of monocytes/macrophages, lymphocytes, activated endothelial cells, granulocytes, and dendritic cells. Its expression is regulated by inflammatory cytokines and can be induced by interleukin 1 (IL-1) and tumor necrosis factor. CD54 is a ligand for LFA-1, a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via CD54/LFA-1 and then transmigrate into tissues. CD54 has been shown to interact with CD11a, EZR, and CD18. More recently, CD54 has been characterized as a site for the cellular entry of human rhinovirus.
Additional information: Clone REA266 displays negligible binding to Fc receptors.

Alternative Names

ICAM-1, BB2, P3.58

Technical specifications

  • Antigen: CD54 (ICAM-1)
  • Clone: REA266
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ICAM-1, BB2, P3.58
  • Entrez Gene ID: 3383
  • Molecular mass of antigen [kDa]: 55
  • Distribution of antigen: monocytes, macrophages, dendritic cells, endothelial cells, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD54 (ICAM-1)-PE, human

  • REA266
  • 1:11
  • For research use only
for 30
tests
(1)
130-103-909
EUR 91,00 

CD54 (ICAM-1)-PE, human

  • REA266
  • 1:11
  • For research use only
for 100
tests
(1)
130-103-839
EUR 240,00 

CD54 (ICAM-1)-APC, human

  • REA266
  • 1:11
  • For research use only
for 30
tests
(1)
130-103-910
EUR 113,00 

CD54 (ICAM-1)-APC, human

  • REA266
  • 1:11
  • For research use only
for 100
tests
(1)
130-103-840
EUR 256,00 

CD54 (ICAM-1)-PE-Vio615, human

  • REA266
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-511
EUR 148,00 

CD54 (ICAM-1)-PE-Vio615, human

  • REA266
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-457
EUR 326,00 

CD54 (ICAM-1)-PE-Vio770, human

  • REA266
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-063
EUR 113,00 

CD54 (ICAM-1)-PE-Vio770, human

  • REA266
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-031
EUR 283,00 

CD54 (ICAM-1)-Biotin, human

  • REA266
  • 1:11
  • For research use only
for 30
tests
(1)
130-103-911
EUR 74,00 

CD54 (ICAM-1)-Biotin, human

  • REA266
  • 1:11
  • For research use only
for 100
tests
(1)
130-103-841
EUR 240,00 

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