CD5 antibodies, mouse

CD5 antibodies, mouse

Clone: REA421 | Dilution: 1:50
Clone REA421 recognizes the mouse CD5 antigen, a 67 kDa single-pass type I membrane protein which is also known as lymphocyte antigen 1 (Ly-1). CD5 is expressed by a majority of thymocytes, mature T cells, and a subset of B cells. The expression of CD5 by a small B cell subset characterizes a developmentally and functionally distinct lineage of B cells called B-1a cells. CD5 plays a role in the interaction of T and B cells and is a counter-receptor for CD72.
Additional information: Clone REA421 displays negligible binding to Fc receptors.

Alternative names

Ly-1, Ly-12, Ly-A, Lyt-1

Technical specifications

  • Antigen: CD5
  • Clone: REA421
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Ly-1, Ly-12, Ly-A, Lyt-1
  • Entrez Gene ID: 12507
  • Molecular mass of antigen [kDa]: 52
  • Distribution of antigen: T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, APC-Vio770
  • Selected references

    1. Tarakhovsky, A. et al. (1995) A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269(5223): 535-537
    2. Efanov, A. et al. (2010)
      CD5
      +
      CD23
      +
      leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation.
      Leukemia 24(5): 970-975
    3. Lundy, S. K. et al. (2014)
      Characterization and activity of Fas ligand producing CD5
      +
      B cells.
      Methods Mol. Biol. 1190: 81-102
Product options: 4
130-120-305

CD5-PE, mouse

30 µg in 200 µL (1)
EUR 80,00 
130-120-231

CD5-PE, mouse

150 µg in 1 mL (1)
EUR 230,00 
130-120-298

CD5-APC, mouse

30 µg in 200 µL (1)
EUR 80,00 
30 µg in 200 µL (1)
EUR 100,00 

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