CD33 antibodies, human

CD33 antibodies, human

Clone: AC104.3E3
Clone AC104.3E3 recognizes the human CD33 antigen, a 67 kDa glycoprotein belonging to the sialoadhesin superfamily. The CD33 antigen is highly expressed on human monocytes but weakly on granulocytes and some – but not all – myeloid dendritic cells. The CD33 antigen is also found on myeloid progenitor cells (CFU-GEMM, CFU GM, CFU-G, BFU-E) but is not expressed on lymphocytes, platelets, erythrocytes, or primitive hematopoietic stem cells.

Alternative names

Siglec-3, p67, My9

Technical specifications

  • Antigen: CD33
  • Clone: AC104.3E3
  • Isotype: mouse IgG1
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Siglec-3, p67, My9
  • Entrez Gene ID: 945
  • Molecular mass of antigen [kDa]: 38
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: basophils, dendritic cells, granulocytes, Langerhans cells, leukemia cells, macrophages, mast cells, monocytes, myeloid cells, NK cells, T cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates:
  • Selected references

    1. Bernstein, I. D. et al. (1987)
      Treatment of acute myeloid leukemia cells
      in vitro
      with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed.
      J. Clin. Invest. 79(4): 1153-1159
Product options: 1
130-108-039

CD33 pure, human

100 µg in 100 µL
EUR 163,00