CD317 (BST2) antibodies, human

CD317 (BST2) antibodies, human

Clone: REA202 | Dilution: 1:11
Clone REA202 recognizes the CD317 antigen, which is a lipid raft-associated type II transmembrane glycoprotein. CD317 is composed of a short N-terminal cytosolic domain, a transmembrane domain, and a C-terminal glycosyl-phosphatidylinositol anchor. Expression of CD317 is upregulated in the presence of IFN-α on T and B cells, is found on the apical surface of polarized epithelial cells, and on myeloma cells. CD317 expression is also found in an intracellular pool and the protein cycles between this intracellular pool and the cell surface in a clathrin dependent manner. It has been shown to play a role in regulating the growth and development of B cells, cell adhesion, cell migration, and in cultured cells. CD317 restricts the release of formed viral particles at the surface of infected cells.
Additional information: Clone REA202 displays negligible binding to Fc receptors.

Alternative Names

BST2, Tetherin, PDCA1, HM1.24

Technical specifications

  • Antigen: CD317 (BST2)
  • Clone: REA202
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: BST2, Tetherin, PDCA1, HM1.24
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    pigtail monkey (
    Macaca nemestrina
    )
  • Distribution of antigen: B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD317 (BST2)-FITC, human

  • REA202
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-658
EUR 74,00 

CD317 (BST2)-FITC, human

  • REA202
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-709
EUR 185,00 

CD317 (BST2)-PE, human

  • REA202
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-656
EUR 91,00 

CD317 (BST2)-PE, human

  • REA202
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-707
EUR 236,00 

CD317 (BST2)-APC, human

  • REA202
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-660
EUR 113,00 

CD317 (BST2)-APC, human

  • REA202
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-714
EUR 255,00 

CD317 (BST2)-PE-Vio770, human

  • REA202
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-654
EUR 113,00 

CD317 (BST2)-PE-Vio770, human

  • REA202
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-702
EUR 278,00 

CD317 (BST2)-APC-Vio770, human

  • REA202
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-659
EUR 101,00 

CD317 (BST2)-APC-Vio770, human

  • REA202
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-711
EUR 278,00 

CD317 (BST2)-Biotin, human

  • REA202
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-131
EUR 50,00 

CD317 (BST2)-Biotin, human

  • REA202
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-093
EUR 236,00 

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