CD300f (IREM-1) antibodies, human

CD300f (IREM-1) antibodies, human

Clone: UP-D2 | Dilution: 1:11
The monoclonal antibody UP-D2 reacts with human CD300f, also known as immune receptor expressed by myeloid cell 1 (IREM-1) which is a type I transmembrane glycoprotein member of the CD300 family. It is expressed on myeloid cells and in peripheral blood on monocytes and granulocytes. IREM-1 binds the p85α regulatory subunit of phosphoinositide 3-kinase (PI3K) and can enhance phagocytosis of apoptotic cells.

Alternative Names

CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Technical specifications

  • Antigen: CD300f (IREM-1)
  • Clone: UP-D2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM
  • Entrez Gene ID: 146722
  • Molecular mass of antigen [kDa]: 30
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, VioBlue, Biotin
  • Selected References

    1. Álvarez-Errico, D. et al. (2007) The IREM-1 (CD300f) inhibitory receptor associates with the p85α subunit of phosphoinositide 3-kinase. J. Immunol. 178: 808-816
    2. Choi, S. C. et al. (2011) Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J. Immunol. 187(7): 3483-3487
    3. Álvarez-Errico, D. et al. (2004) IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Eur. J. Immunol. 34(12): 3690-3701
Product options: 4

Product information

Size
Order no.
Price

CD300f (IREM-1)-FITC, human

  • UP-D2
  • 1:11
  • For research use only
for 100
tests
(1)
130-098-443
EUR 187,00 

CD300f (IREM-1)-APC, human

  • UP-D2
  • 1:11
  • For research use only
for 100
tests
(1)
130-098-471
EUR 256,00 

CD300f (IREM-1)-VioBlue, human

  • UP-D2
  • 1:11
  • For research use only
for 100
tests
(1)
130-098-433
EUR 245,00 

CD300f (IREM-1)-Biotin, human

  • UP-D2
  • 1:11
  • For research use only
for 100
tests
(1)
130-098-475
EUR 240,00