CD267 (TACI) antibodies, human

CD267 (TACI) antibodies, human

Clone: 1A1 | Dilution: 1:11
Clone 1A1 recognizes human CD267, a 32 kDa type III transmembrane protein belonging to the TNF receptor superfamily. CD267 as receptor binds to BAFF and APRIL and plays an important role in the stimulation of B and T cell–function and in the regulation of humoral immunity. CD267 expression is found in CD27
memory B cells, tonsillar and bone marrow plasma cells, in a subpopulation of activated CD27
, non-GC cells, and in a small subset of naive blood and tonsil B cells. CD267 is also expressed on many lymphomas such as multiple myeloma and Hodgkin and non-Hodgkin lymphomas. Mutations in CD267 are often associated with common variable immunodeficiency in humans. Signaling via CD267 leads to activation of the transcription factors NFAT, AP1, and NF-κB.

Alternative names


Technical specifications

  • Antigen: CD267 (TACI)
  • Clone: 1A1
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: TNFRSF13B, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B
  • Entrez Gene ID: 23495
  • Molecular mass of antigen [kDa]: 32
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, Biotin
  • Selected references

    1. Salzer, U. et al. (2005) Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nat. Genet. 37(8): 820-828
    2. Mackay, F. et al. (2008) TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine Growth Factor Rev. 19(3–4): 263-276
Product options: 4
for 30
EUR 113,00 
for 100
EUR 273,00 
for 30
EUR 93,00 
for 100
EUR 227,00 

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