CD202b (TIE-2) antibodies, mouse

CD202b (TIE-2) antibodies, mouse

Clone: REA735 | Dilution: 1:50
Clone REA735 recognizes the CD202b antigen, also known as TIE-2 or TEK. CD202b is a tyrosine-protein kinase which is mainly expressed in endothelial cells and their progenitors. CD202b is a cell-surface receptor for angiopoietins and is involved in angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, and re-organization of the actin cytoskeleton.
Additional information: Clone REA735 displays negligible binding to Fc receptors.

Alternative Names

HYK, STK1, TIE-2, TIE2, TEK

Technical specifications

  • Antigen: CD202b (TIE-2)
  • Clone: REA735
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: HYK, STK1, TIE-2, TIE2, TEK
  • Entrez Gene ID: 21687
  • Molecular mass of antigen [kDa]: 124
  • Distribution of antigen: endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC
  • Selected References

    1. Dumont, D. J. et al. (1993) The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. Oncogene 8(5): 1293-1301
    2. Jones, N. et al. (1999) Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration. J. Biol. Chem. 274(43): 30896-30905
    3. Fiedler, U. et al. (2003) Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. J. Biol. Chem. 278(3): 1721-1727
Product options: 6
130-112-019

CD202b (TIE-2)-VioBright FITC, mouse

30 µg in 200 µL (1)
EUR 100,00 
130-111-867

CD202b (TIE-2)-VioBright FITC, mouse

150 µg in 1 mL (1)
EUR 295,00 
130-112-017

CD202b (TIE-2)-PE, mouse

30 µg in 200 µL (1)
EUR 80,00 
130-111-865

CD202b (TIE-2)-PE, mouse

2×150 µg in 1 mL (1)
EUR 275,00 
130-112-018

CD202b (TIE-2)-APC, mouse

30 µg in 200 µL (1)
EUR 80,00 
130-111-866

CD202b (TIE-2)-APC, mouse

150 µg in 1 mL (1)
EUR 230,00