CD2 antibodies, human

CD2 antibodies, human

Clone: REA972 | Dilution: 1:50
Clone REA972 recognizes the human CD2 antigen, a 50 kDa single-chain transmembrane glycoprotein also known as LFA-2 or receptor for sheep erythrocytes. CD2 functions as a costimulatory molecule on T and natural killer (NK) cells and is a receptor for other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58). It belongs to the Ig superfamily and is involved in cell signaling and lymphocyte adhesion. The CD2 antibody reacts with 80–90% of peripheral blood lymphocytes and more than 95% of thymocytes and recognizes all T cells and a subset of NK cells.
Additional information: Clone REA972 displays negligible binding to Fc receptors.

Alternative names

LFA-2, SRBC-R, T11, SRBC

Technical specifications

  • Antigen: CD2
  • Clone: REA972
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LFA-2, SRBC-R, T11, SRBC
  • Entrez Gene ID: 914
  • Molecular mass of antigen [kDa]: 37
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: B cells, lymphocytes, macrophages, mast cells, NK cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770
  • Selected references

    1. Sanchez-Madrid, F. et al. (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U.S.A. 79: 7489-7493
    2. Ozwara, H. et al. (1997)
      Flow cytometric analysis on reactivity of human T lymphocyte-specific and cytokine-receptor-specific antibodies with peripheral blood mononuclear cells of chimpanzee (
      Pan troglodytes
      ), rhesus macaque (
      Macacca mulatta
      ) and squirrel monkey (
      Saimiri sciureus
      ).
      J. Med. Primatol. 26(3): 164-171
Product options: 12
130-116-251

CD2-FITC, human

for 30
tests
(1)
EUR 90,00 
130-116-148

CD2-FITC, human

for 100
tests
(1)
EUR 220,00 
130-116-252

CD2-PE, human

for 30
tests
(1)
EUR 110,00 
130-116-149

CD2-PE, human

for 100
tests
(1)
EUR 265,00 
130-116-253

CD2-APC, human

for 30
tests
(1)
EUR 110,00 
130-116-150

CD2-APC, human

for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 

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