CD186 (CXCR6) antibodies, human

CD186 (CXCR6) antibodies, human

Clone: REA458
Clone REA458 recognizes the human CD186 antigen, a multi-pass membrane protein which is also known as C-X-C chemokine receptor type 6 (CXCR6), STRL33, or bonzo. CD186 is expressed on a subset of type 1 polarized peripheral blood CD4
and CD8
T cells, γδ T cells, natural killer T cells, natural killer cells, monocytes, and B cells. It is induced in activated peripheral blood lymphocytes. The ligand of CD186 is the chemokine CXCL16. CD186 is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
Additional information: Clone REA458 displays negligible binding to Fc receptors.

Alternative names


Technical specifications

  • Antigen: CD186 (CXCR6)
  • Clone: REA458
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CXCR6, BONZO, STRL33, TYMSTR
  • Entrez Gene ID: 10663
  • Molecular mass of antigen [kDa]: 39
  • Distribution of antigen: T cells, NKT cells, NK cells, monocytes, B cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 100 µL
EUR 207,00