CD180 (RP105) antibodies, human

CD180 (RP105) antibodies, human

Clone: REA956 | Dilution: 1:50
Clone REA956 recognizes the human CD180 antigen, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. RP105 is expressed on mature B cells in mantle zones as well as on monocytes, macrophages, and dendritic cells.
Additional information: Clone REA956 displays negligible binding to Fc receptors.

Alternative Names

LY64, Ly78, RP105

Technical specifications

  • Antigen: CD180 (RP105)
  • Clone: REA956
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LY64, Ly78, RP105
  • Entrez Gene ID: 4064
  • Molecular mass of antigen [kDa]: 72
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: dendritic cells, macrophages, monocytes, plasma cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected References

    1. Miura, Y. et al. (1998) RP105 Is associated with MD-1 and transmits an activation signal in human B cells. Blood 92: 2815-2822
    2. Ogata, H. et al. (2000) The toll-like receptor protein Rp105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192: 23-30
    3. Divanovic, S. et al. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat. Immunol. 6(6): 571-578

Related products

2 products available
Product options: 14
130-115-920

CD180 (RP105)-PE, human

for 30
tests
(1)
EUR 110,00 
130-115-848

CD180 (RP105)-PE, human

for 100
tests
(1)
EUR 265,00 
130-115-921

CD180 (RP105)-APC, human

for 30
tests
(1)
EUR 110,00 
130-115-849

CD180 (RP105)-APC, human

for 100
tests
(1)
EUR 265,00 
130-115-926

CD180 (RP105)-PE-Vio615, human

for 30
tests
(1)
EUR 120,00 
130-115-854

CD180 (RP105)-PE-Vio615, human

for 100
tests
(1)
EUR 290,00 
130-115-922

CD180 (RP105)-PE-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-115-850

CD180 (RP105)-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-115-923

CD180 (RP105)-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-115-851

CD180 (RP105)-APC-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-115-924

CD180 (RP105)-PerCP-Vio700, human

for 30
tests
(1)
EUR 120,00 
130-115-852

CD180 (RP105)-PerCP-Vio700, human

for 100
tests
(1)
EUR 290,00 
130-115-918

CD180 (RP105)-Biotin, human

for 30
tests
(1)
EUR 90,00 
130-115-846

CD180 (RP105)-Biotin, human

for 100
tests
(1)
EUR 220,00