CD18 antibodies, human

CD18 antibodies, human

Clone: REA1112 | Dilution: 1:50
Clone REA1112 recognizes the human CD18 antigen, a type I transmembrane protein with an approximate molecular weight of 90–95 kDa. It non-covalently associates with α subunits CD11a (αL), CD11b (αM), CD11c (αX), and CD11d (αD) to form functional integrins which are expressed on leukocytes. CD18 associated integrins bind several ligands including cell surface and extracellular matrix proteins and are involved in cell-cell and cell-extracellular matrix interactions, immune regulation, and immune tolerance. Leucocytes of patients lacking CD18 or expressing dysfunctional CD18 are defective in chemotaxis, phagocytosis, and homotypic aggregation.
Additional information: Clone REA1112 displays negligible binding to Fc receptors.

Alternative Names

ITGB2, LAD, LCAMB, LFA-1, Mac-1 α, MF17

Technical specifications

  • Antigen: CD18
  • Clone: REA1112
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGB2, LAD, LCAMB, LFA-1, Mac-1 α, MF17
  • Entrez Gene ID: 3689
  • Molecular mass of antigen [kDa]: 83
  • Cross-reactivity: porcine
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE-Vio615, PE-Vio770
Product options: 4

Product information

Size
Order no.
Price

CD18-PE-Vio615, human

  • REA1112
  • 1:50
  • For research use only
for 30
tests
(1)
130-119-264
EUR 111,00 

CD18-PE-Vio615, human

  • REA1112
  • 1:50
  • For research use only
for 100
tests
(1)
130-119-090
EUR 300,00 

CD18-PE-Vio770, human

  • REA1112
  • 1:50
  • For research use only
for 30
tests
(1)
130-119-265
EUR 111,00 

CD18-PE-Vio770, human

  • REA1112
  • 1:50
  • For research use only
for 100
tests
(1)
130-119-091
EUR 300,00