CD16 antibodies, human

CD16 antibodies, human

Clone: VEP13 | Dilution: 1:50
CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils.
The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes.

Alternative Names

FcγRIIIA, FcγRIIIB, FcR-10, IGFR3, IMD20

Technical specifications

  • Antigen: CD16
  • Clone: VEP13
  • Isotype: mouse IgMκ
  • Isotype control: Mouse IgM – isotype control antibodies
  • Alternative names of antigen: FcγRIIIA, FcγRIIIB, FcR-10, IGFR3, IMD20
  • Entrez Gene ID: 2214
  • Molecular mass of antigen [kDa]: 20-27
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: eosinophils, granulocytes, macrophages, mast cells, monocytes, myeloid cells, neutrophils, NK cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin
Product options: 2

Product information

Size
Order no.
Price

CD16-Biotin, human

  • VEP13
  • 1:50
  • For research use only
for 30
tests
(1)
130-113-944
EUR 86,00 

CD16-Biotin, human

  • VEP13
  • 1:50
  • For research use only
for 100
tests
(1)
130-113-382
EUR 252,00 

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