CD158i (KIR2DS4) antibodies, human

CD158i (KIR2DS4) antibodies, human

Clone: JJC11.6 | Dilution: 1:11
Clone JJC11.6 recognizes CD158i (KIR2DS4), a member of the killer immunoglobulin-like receptor (KIR) family expressed on natural killer (NK) cells. CD158i (KIR2DS4) provides an activation signal for NK lytic activity upon interaction with its ligand, HLA-Cw4, in an antigen-independent manner.
KIRs are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. The receptor family can be subdivided functionally according to the length of their cytoplasmic tail in inhibitory and activating KIRs.

Alternative Names

KIR2DS4

Technical specifications

  • Antigen: CD158i (KIR2DS4)
  • Clone: JJC11.6
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: KIR2DS4
  • Entrez Gene ID: 3809
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin, pure
  • Selected References

    1. Kratz, G. et al. (2004) MHC Class I-independent recognition of NK-activating receptor KIR2DS4. J. Immunol. 173: 1819-1825
    2. Djeu, J. et al. (2002) A view to a kill: signals triggering cytotoxicity. Clin. Cancer Res. 8: 636-640
    3. Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52
    4. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196
Product options: 8

Product information

Size
Order no.
Price

CD158i (KIR2DS4)-PE, human

  • JJC11.6
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-698
EUR 91,00 

CD158i (KIR2DS4)-PE, human

  • JJC11.6
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-680
EUR 240,00 

CD158i (KIR2DS4)-APC, human

  • JJC11.6
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-709
EUR 113,00 

CD158i (KIR2DS4)-APC, human

  • JJC11.6
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-681
EUR 256,00 

CD158i (KIR2DS4)-PE-Vio770, human

  • JJC11.6
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-963
EUR 113,00 

CD158i (KIR2DS4)-PE-Vio770, human

  • JJC11.6
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-962
EUR 278,00 

CD158i (KIR2DS4)-Biotin, human

  • JJC11.6
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-898
EUR 240,00 

CD158i (KIR2DS4) pure, human

  • JJC11.6
  • For research use only
100 µg in 1 mL
130-092-679
EUR 198,00