CD152  antibodies – functional grade, human

CD152 antibodies – functional grade, human

Clone: BNI3
The monoclonal antibody BNI3 reacts with human CD152, an integral membrane protein of the immunoglobin superfamily which is also called CTLA-4. CD152 is a negative regulator of T cell activation. It is transiently expressed on activated CD28
+
T cells and is a ligand for CD80 and CD86. CD4
+
FoxP3
+
regulatory T cells are reported to constitutively express CD152. CD152 may also be detected on B cells when cultured with activated T cells.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

CTLA4, ALPS5, CD, CELIAC3, CTLA-4, GRD4, GSE, IDDM12

Technical specifications

  • Antigen: CD152
  • Clone: BNI3
  • Isotype: mouse IgG2aκ
  • Alternative names of antigen: CTLA4, ALPS5, CD, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
  • Entrez Gene ID: 1493
  • Molecular mass of antigen [kDa]: 21
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: B cells, lymphocytes, T cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD152 pure - functional grade, human

  • BNI3
  • For research use only
500 µg in 0.5 mL
130-106-228
EUR 330,00 

Related products

1 products available