CD15 antibodies, human

CD15 antibodies, human

Clone: VIMC6 | Dilution: 1:11
The CD15 antibody recognizes the CD15 antigen which is expressed on human myelomonocytic cells. It is present on neutrophils, eosinophils, and some monocytes, but not on basophils or lymphocytes. The antigen is also expressed on Hodgkin/Reed-Sternberg cells.
The CD15 antibody recognizes the carbohydrate structure 3-fucosyl-N-acetyl-lactosamine. This structure is also known as stage specific embryonic antigen 1 (SSEA-1) and a common surface marker for pluripotency on mouse ES and iPS cells. On human cells in contrast, SSEA-1 is expressed only on early differentiating cells. The CD15 antibody recognizes the SSEA-1 antigen in both species. For applications in ES and iPS research, the dilution recommended in the data sheet may need adjustment.

Alternative names

FUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X

Technical specifications

  • Antigen: CD15
  • Clone: VIMC6
  • Isotype: mouse IgM
  • Isotype control: Mouse IgM – isotype control antibodies
  • Alternative names of antigen: FUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X
  • Distribution of antigen: B cells, basophils, bone marrow, brain, breast, cancer stem cells, eosinophils, epithelial cells, granulocytes, kidney, Langerhans cells, leukemia cells, lung, monocytes, myeloid cells, neutrophils, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin
  • Selected references

    1. Choi, K.-D. et al. (2011) Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells. Nat. Protoc. 6(3): 296-313
Product options: 1
130-098-383

CD15-Biotin, human

for 100
tests
(1)
EUR 220,00