CD147 antibodies, human

CD147 antibodies, human

Clone: REA282 | Dilution: 1:50
Clone REA282 recognizes the human CD147 antigen, a single-pass type I membrane protein which is also known as basigin (BSG) or extracellular matrix metalloproteinase inducer (EMMPRIN). CD147 is expressed by many cell types, including epithelial cells, endothelial cells, leukocytes, and tumor cells. It is present in vascular endothelium in non-neoplastic regions of the brain and in tumor cells, but not in proliferating blood vessels in malignant gliomas. CD147 has been implicated in a variety of physiological and pathological activities. It is best known for its ability to function as extracellular matrix metalloproteinase inducer, but has also been shown to regulate lymphocyte responsiveness, monocarboxylate transporter expression, and spermatogenesis.
Additional information: Clone REA282 displays negligible binding to Fc receptors.

Alternative names

BSG, 5F7, EMMPRIN, M6, OK, TCSF, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor (TCSF)

Technical specifications

  • Antigen: CD147
  • Clone: REA282
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: BSG, 5F7, EMMPRIN, M6, OK, TCSF, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor (TCSF)
  • Entrez Gene ID: 682
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: epithelial cells, endothelial cells, leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
  • Selected references

    1. Kasinrerk, W. et al. (1992) Human leukocyte activation antigen M6, a member of the Ig superfamily, is the species homologue of rat OX-47, mouse basigin, and chicken HT7 molecule. J. Immunol. 149(3): 847-854
    2. Biswas, C. et al. (1995) The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res. 55(2): 434-439
    3. Yurchenko, V. et al. (2006) Dealing with the family: CD147 interactions with cyclophilins. Immunology 117(3): 301-309
Product options: 2
for 30
EUR 93,00 
for 100
EUR 227,00 

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