CD11b antibodies, human

CD11b antibodies, human

Clone: REA713 | Dilution: 1:50
Clone REA713 recognizes the human CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain.
Additional information: Clone REA713 displays negligible binding to Fc receptors.

Alternative Names

integrin αM, Mac-1 α, Integrin alpha-M, CR3A

Technical specifications

  • Antigen: CD11b
  • Clone: REA713
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: integrin αM, Mac-1 α, Integrin alpha-M, CR3A
  • Entrez Gene ID: 3684, 16409
  • Molecular mass of antigen [kDa]: 126
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon,
    common marmoset (
    Callithrix jacchus
    )
    , pig, porcine
  • Distribution of antigen: myeloid cells, NK cells, microglia, brain, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA713
ICRF44++
M1/70-
M1/70.15.11.5+
CBRM1/5-
REA592-
Product options: 18

Product information

Size
Order no.
Price

CD11b-FITC, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-610
EUR 86,00 

CD11b-FITC, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-552
EUR 252,00 

CD11b-PE, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-611
EUR 112,00 

CD11b-PE, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-553
EUR 296,00 

CD11b-APC, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-612
EUR 146,00 

CD11b-APC, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-554
EUR 322,00 

CD11b-VioBlue, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-616
EUR 112,00 

CD11b-VioBlue, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-558
EUR 296,00 

CD11b-VioGreen, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-617
EUR 146,00 

CD11b-VioGreen, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-559
EUR 322,00 

CD11b-PE-Vio770, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-613
EUR 146,00 

CD11b-PE-Vio770, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-555
EUR 322,00 

CD11b-APC-Vio770, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-614
EUR 129,00 

CD11b-APC-Vio770, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-556
EUR 308,00 

CD11b-PerCP-Vio700, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-615
EUR 129,00 

CD11b-PerCP-Vio700, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-557
EUR 308,00 

CD11b-Biotin, human

  • REA713
  • 1:50
  • For research use only
for 30
tests
(1)
130-110-609
EUR 86,00 

CD11b-Biotin, human

  • REA713
  • 1:50
  • For research use only
for 100
tests
(1)
130-110-551
EUR 252,00 

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