Anti-SIT1 antibodies, human

Anti-SIT1 antibodies, human

Clone: REA864 | Dilution: 1:50
Clone REA864 recognizes the human SIT1 antigen, a disulfide-linked homodimeric glycoprotein also known as SHP2 interacting transmembrane adaptor protein or suppression-inducing transmembrane adapter 1. SIT1 is expressed in lymphocytes and predominantly found in T and B cells as well as in plasma cells.
SIT1 plays a regulatory role in T cell activation and development. In association with Grb2 and SHP2, it is involved in signal transduction.
Additional information: Clone REA864 displays negligible binding to Fc receptors.

Alternative names

SIT

Technical specifications

  • Antigen: SIT1
  • Clone: REA864
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: SIT
  • Entrez Gene ID: 27240
  • Molecular mass of antigen [kDa]: 19
  • Cross-reactivity: mouse
  • Distribution of antigen: plasma cells, T cells, B cells, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Vio515
  • Selected references

    1. Marie-Cardine, A. et al. (1999) SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation. J. Exp. Med. 189(8): 1181-1194
    2. Tedoldi, S. et al. (2006) Transmembrane adaptor molecules: a new category of lymphoid-cell markers. Blood 107(1): 213-221
Product options: 8
130-114-392

Anti-SIT1-FITC, human

for 30
tests
(1)
EUR 90,00 
130-114-285

Anti-SIT1-FITC, human

for 100
tests
(1)
EUR 220,00 
130-114-393

Anti-SIT1-PE, human

for 30
tests
(1)
EUR 110,00 
130-114-286

Anti-SIT1-PE, human

for 100
tests
(1)
EUR 265,00 
130-114-394

Anti-SIT1-APC, human

for 30
tests
(1)
EUR 110,00 
130-114-287

Anti-SIT1-APC, human

for 100
tests
(1)
EUR 265,00 
130-114-395

Anti-SIT1-Vio515, human

for 30
tests
(1)
EUR 115,00 
130-114-288

Anti-SIT1-Vio515, human

for 100
tests
(1)
EUR 275,00