Anti-PSMA antibodies, human

Anti-PSMA antibodies, human

Clone: REA408 | Dilution: 1:50
Clone REA408 recognizes the human prostate-specific membrane antigen (PSMA) antigen, a single-pass type II membrane protein which is also known as folate hydrolase 1 (FOLH1), glutamate carboxypeptidase 2 (GCP2), or N-acetylated-alpha-linked acidic dipeptidase I (NAALADase). PSMA is a zinc metallopeptidase which catalyzes the hydrolysis of N-acetylaspartylglutamate to glutamate and N-acetylaspartate. It is expressed with low levels in the small intestine, renal tubular cells, and salivary gland, and is over-expressed in prostate cancer tissue. PSMA is also expressed in the nervous system.
Additional information: Clone REA408 displays negligible binding to Fc receptors.

Alternative names

FOLH1, FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, mGCP, NAALADase I

Technical specifications

  • Antigen: PSMA
  • Clone: REA408
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FOLH1, FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, mGCP, NAALADase I
  • Entrez Gene ID: 2346
  • Molecular mass of antigen [kDa]: 84
  • Distribution of antigen: small intestine, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, APC, Biotin
  • Selected references

    1. Israeli, R. S. et al. (1993) Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen. Cancer Res. 53(2): 227-230
    2. Ghosh, A. et al. (2004) Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancer. J. Cell. Biochem. 91(3): 528-539
    3. Luthi-Carter, R. et al. (1998) Molecular characterization of human brain N-acetylated alpha-linked acidic dipeptidase (NAALADase). J. Pharmacol. Exp. Ther. 286(2): 1020-1025
Product options: 6
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 270,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 230,00 

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