Anti-HLA-A3, human

Anti-HLA-A3, human

Clone: REA950 | Dilution: 1:50
Clone REA950 recognizes the human major histocompatibility complex (MHC) class I molecule HLA-A3, a heterodimer belonging to the HLA-A family and consisting of two subtypes, A3.1 and A3.2. HLA-A has a heavy chain (anchored in the membrane) and a light chain (beta-2 microglobulin). MHC class I molecules are expressed on nearly all nucleated cells and present small intracellular peptides on the cell surface to the immune system. The peptids are recognized by circulating CD8
+
cytotoxic T lymphocytes.
Additional information: Clone REA950 displays negligible binding to Fc receptors.

Alternative names

HLAA

Technical specifications

  • Antigen: HLA-A3
  • Clone: REA950
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLAA
  • Entrez Gene ID: 3105
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770
  • Selected references

    1. Jelachich, M. L. et al. (1988) Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule. J. Immunol. 141(4): 1108-1113
    2. Vonderheide, R. H. et al. (2001) Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin. Cancer Res. 7(11): 3343-3348
Product options: 12
130-115-793

Anti-HLA-A3-FITC, human

for 30
tests
(1)
EUR 90,00 
130-115-739

Anti-HLA-A3-FITC, human

for 100
tests
(1)
EUR 220,00 
130-115-794

Anti-HLA-A3-PE, human

for 30
tests
(1)
EUR 110,00 
130-115-740

Anti-HLA-A3-PE, human

for 100
tests
(1)
EUR 265,00 
130-115-795

Anti-HLA-A3-APC, human

for 30
tests
(1)
EUR 110,00 
130-115-741

Anti-HLA-A3-APC, human

for 100
tests
(1)
EUR 265,00 
130-115-917

Anti-HLA-A3-PE-Vio615, human

for 30
tests
(1)
EUR 120,00 
130-115-845

Anti-HLA-A3-PE-Vio615, human

for 100
tests
(1)
EUR 290,00 
130-115-796

Anti-HLA-A3-PE-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-115-742

Anti-HLA-A3-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-115-797

Anti-HLA-A3-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-115-743

Anti-HLA-A3-APC-Vio770, human

for 100
tests
(1)
EUR 290,00