Anti-Cardiac Troponin T antibodies, human, mouse, rat

Anti-Cardiac Troponin T antibodies, human, mouse, rat

Clone: REA400 | Dilution: 1:10
Clone REA400 recognizes the human, mouse, and rat cardiac troponin T antigen, a protein which is exclusively expressed at high concentrations in cardiac muscle and has emerged as the preferred biomarker in the universal definition of myocardial infarction. Cardiac troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the cardiac troponin T gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms. Mutations of this gene may be associated with mild or absent hypertrophy and predominant restrictive disease, with a high risk of sudden cardiac death. Pluripotent stem cells (PSCs) differentiate into cardiomyocytes positive for cardiac troponin T and showing spontaneous rhythmic contractions. Therefore, PSC-derived cardiomyocytes have emerged as a potential source for cardiac regeneration after myocardial infarction.
Additional information: Clone REA400 displays negligible binding to Fc receptors.

Alternative Names

TNNT2, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTc, cTnT

Technical specifications

  • Antigen: Cardiac Troponin T
  • Clone: REA400
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: TNNT2, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTc, cTnT
  • Entrez Gene ID: 7139, 21956, 24837
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: cardiac muscle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, VioBlue, Biotin, pure
Product options: 7

Product information

Size
Order no.
Price

Anti-Cardiac Troponin T-APC, human, mouse, rat

  • REA400
  • 1:10
  • For research use only
for 30
tests
(1)
130-106-747
EUR 146,00 

Anti-Cardiac Troponin T-APC, human, mouse, rat

  • REA400
  • 1:10
  • For research use only
for 100
tests
(1)
130-106-689
EUR 322,00 

Anti-Cardiac Troponin T-VioBlue, human, mouse, rat

  • REA400
  • 1:10
  • For research use only
for 30
tests
(1)
130-106-744
EUR 110,00 

Anti-Cardiac Troponin T-VioBlue, human, mouse, rat

  • REA400
  • 1:10
  • For research use only
for 100
tests
(1)
130-106-686
EUR 292,00 

Anti-Cardiac Troponin T-Biotin, human, mouse, rat

  • REA400
  • 1:10
  • For research use only
for 30
tests
(1)
130-106-743
EUR 86,00 

Anti-Cardiac Troponin T-Biotin, human, mouse, rat

  • REA400
  • 1:10
  • For research use only
for 100
tests
(1)
130-106-685
EUR 252,00 

Anti-Cardiac Troponin T pure, human, mouse, rat

  • REA400
  • For research use only
100 µg in 100 µL
130-112-756
EUR 144,00 

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