CD140a (PDGFRα) MicroBead Kit, mouse

CD140a (PDGFRα) MicroBead Kit, mouse

The CD140a (PDGFRα) MicroBead Kit was developed for the direct isolation or depletion of CD140a (PDGFRα) positive oligodendrocyte precursors from dissociated mouse brain tissue.

Background information

CD140a (PDGFRα) MicroBeads (PDGFRα: platelet-derived growth factor receptor alpha) have been developed for the separation of mouse cells based on the expression of the CD140a (PDGFRα) antigen. CD140a (PDGFRα) has been reported to be broadly expressed in embryonic tissue, various malignancies and embryonic stem cell-derived cardiomyogenic cells.
1,2
Furthermore, CD140a (PDGFRα) is specifically expressed by oligodendrocyte precursor cells, which differentiate into myelinating oligodendrocytes.
3–5
CD140a (PDGFRα) MicroBeads were especially optimized for the separation of oligodendrocyte progenitor cells (OPCs) based on the expression of CD140a (PDGFRα). The isolation was tested particularly on dissociated postnatal CD1 mouse brain tissue derived from animals younger than postnatal day eight (P8). In principle, cell isolation is also possible from older mice, but purity of the positive fraction might be lower due to lower frequency of CD140a (PDGFRα) positive cells after tissue dissociation.
For optimal results, the Neural Tissue Dissociation Kit (P) is recommended prior to cell isolation.
Product options: 2

Product information

Size
Order no.
Price

CD140a (PDGFRα) MicroBead Kit, mouse - small size

  • For research use only
for 5×
10
7
total cells
130-101-547
EUR 68,00 

CD140a (PDGFRα) MicroBead Kit, mouse

  • For research use only
for 1×
10
9
total cells
130-101-502
EUR 641,00 

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