CD209 (DC-SIGN) MicroBead Kit, human

CD209 (DC-SIGN) MicroBead Kit, human

The CD209 (DC-SIGN) MicroBead Kit has been developed for the magnetic separation of human CD209

Background information

CD209 (Dendritic Cell Specific ICAM-3 Grabbing Non-integrin, DC-SIGN) is a type II C-type lectin receptor. It is expressed on DCs in dermal and mucous tissue, in lymphoid tissue such as tonsil, lymph node, and spleen, and on monocyte-derived DCs (Mo-DCs). It is not expressed on DC subsets in peripheral blood, except for a subpopulation of CD14
cells with DC-like phenotype. DC-SIGN acts as an adhesion receptor to facilitate interactions between DCs and T cells or DCs and endothelial cells. In addition, it serves as an antigen receptor to mediate internalization of ligands for antigen presentation, binding viruses such as HIV, HCMV, or Ebola as well as parasites, bacteria, or yeast.


The CD209 (DC-SIGN) MicroBead Kit can be used for positive selection or depletion of cells expressing the human CD209 (DC-SIGN) antigen.


For positive selection: MS, LS, XS, or autoMACS
Columns. For depletion: LD, D, or autoMACS Columns.
  • Selected references

    1. Koppel, E. A. et al. (2005) Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation. Cell. Microbiol. 7: 157-165
Product options: 1
for 2×
total cells
EUR 764,00 

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