GM-CSF Secretion Assay – Cell Enrichment and Detection Kit (PE), human

GM-CSF Secretion Assay – Cell Enrichment and Detection Kit (PE), human

The GM-CSF Secretion Assay - Cell Enrichment and Detection Kit was developed for enrichment and sensitive detection of human GM-CSF-secreting cells.

Background information

Granulocyte macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor that is essential for proliferation and development of granulocyte and monocyte/macrophage progenitors. It also functions as a growth factor for erythroid and megakaryocytic precursor cells in conjunction with erythropoietin. GM-CSF is secreted by various cell types including T cells, macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli and cytokines. In addition, GM-CSF strongly chemoattracts neutrophils and eosinophils and enhances the effector functions of neutrophils and macrophages.

Downstream applications

  • Enrichment and detection of viable GM-CSF–secreting leukocytes.
  • Enrichment and detection of viable GM-CSF–secreting leukocytes from whole blood.
  • Enrichment and detection of GM-CSF–secreting, antigen-specific T cells for enumeration and phenotypic characterization as well as for expansion and functional characterization.
  • Monitoring and analysis of very low frequent antigen-specific T cell immunity in autoimmunity.
  • Isolation and expansion of antigen-specific T cells.
  • Enrichment and analysis of GM-CSF–secreting cells for determination of functional antigens in disease and for T cell receptor (TCR) epitope mapping.
  • Analysis or cloning of TCR repertoire of antigen-specific T cells.

Columns

MS, LS, or autoMACS
®
Columns.
Product options: 1

Product information

Size
Order no.
Price

GM-CSF Secretion Assay – Cell Enrichment and Detection Kit (PE), human

  • For research use only
for 50
tests
(1)
130-105-760
EUR 800,00 

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