StemMACS™ IWR-1-endo

StemMACS™ IWR-1-endo

StemMACS™ IWR-1-endo is an inhibitor of the Wnt signaling pathway.

Background information

StemMACS™ IWR-1-endo is a potent inhibitor of the Wnt signaling pathway. It stabilizes the Axin-scaffolded destruction complex, thereby promoting β-catenin phosphorylation and degradation. In cell culture reporter assays IWR-1-endo inhibits Wnt/β-catenin signaling with an IC50 value of 180 nM.


Published applications for IWR-1-endo include:
  • Cardiac differentiation of human PSCs1, 2
  • Differentiaton of human PSCs into alveolar epithelial cells3
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Product information

Order no.

StemMACS IWR-1-endo

  • For research use only
5 mg
EUR 99,00