StemMACS™ IWR-1-endo

StemMACS™ IWR-1-endo

StemMACS™ IWR-1-endo is an inhibitor of the Wnt signaling pathway.

Background information

StemMACS™ IWR-1-endo is a potent inhibitor of the Wnt signaling pathway. It stabilizes the Axin-scaffolded destruction complex, thereby promoting β-catenin phosphorylation and degradation. In cell culture reporter assays IWR-1-endo inhibits Wnt/β-catenin signaling with an IC50 value of 180 nM.

Applications

Published applications for IWR-1-endo include:
  • Cardiac differentiation of human PSCs1, 2
  • Differentiaton of human PSCs into alveolar epithelial cells3
Product options: 1

Product information

Size
Order no.
Price

StemMACS IWR-1-endo

  • For research use only
5 mg
130-110-491
EUR 99,00