Clone:
AT-8
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2aκ
Applications:
FC
Alternative names:
Klra7, LGL-1, Ly49G.4, Ly49g1, Ly-49G2, Kira-7

Specifications for Ly-49G Antibody, anti-mouse

Overview

The monoclonal antibody AT-8 recognizes the type II transmembrane protein Ly-49G, which is a MHC class I receptor also known as Kira-7. It is expressed on NK, NKT, and T cells. It is reported that the binding of Ly-49G with its ligand leads to inhibition of NK cells, T cells cytotoxicity, cytokine production, and proliferation. The antibody reacts with Ly-49G receptor of A/J, BALB/c, C3H, CBA,129, FVB, and SJL mice, but not C57BL/6 mice.

Alternative names

Klra7, LGL-1, Ly49G.4, Ly49g1, Ly-49G2, Kira-7

Detailed product information

Technical specifications

CloneAT-8
Clonalitymonoclonal
Isotypemouse IgG2aκ
Isotype controlIsotype Control Antibody, mouse IgG2a
Hostmouse
Type of antibodyPrimary antibodies
Speciesmouse
AntigenLy-49G
Alternative names of antigenKlra7, LGL-1, Ly49G.4, Ly49g1, Ly-49G2, Kira-7
Molecular mass of antigen [kDa]33
Entrez Gene ID16638
RRIDAB_2652754, AB_2652755, AB_2652756, AB_2652753

References for Ly-49G Antibody, anti-mouse

Publications

  1. Makrigiannis, A. P. et al. (2004) Independent control of Ly49g alleles: implications for NK cell repertoire selection and tumor cell killing. J. Immunol. 172: 1414-1425
  2. Rouhi, A. et al. (2007) Plasticity of Ly49g expression is due to epigenetics. Mol. Immunol. 44(5): 821-826

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Ly-49G Antibody, anti-mouse

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