Clone:
MQ2-13A5
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
rat IgG1κ, rat IgG1
Applications:
MC, FA, ICFC
Alternative names:
BSF2, HGF, HSF, IFNB2

Extended validation for IL-6 Antibody, anti-human

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with MQ2-13A5
REA1037++
AS12-
MQ2-6A3-
Cells were incubated with an excess of purified unconjugated IL-6 (MQ2-13A5) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for IL-6 Antibody, anti-human

Overview

Interleukin 6 (IL-6), originally identified as a B cell differentiation factor, is a multifunctional cytokine, which regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions. It induces the terminal maturation of activated B cells into antibody-secreting plasma cells and acts in synergy with IL-3 to support the proliferation of hematopoietic stem cells. IL-6 is produced by many cell types, such as monocytes, fibroblasts, endothelial cells, eosinophils, and T cells. Disturbed IL-6 production has been associated with pathological processes, including inflammatory autoimmune diseases and cancer.

Alternative names

BSF2, HGF, HSF, IFNB2

Detailed product information

Technical specifications

CloneMQ2-13A5
Clonalitymonoclonal
Isotyperat IgG1, rat IgG1κ
Isotype controlIsotype Control Antibody, rat IgG1
Hostrat
Type of antibodyPrimary antibodies, Functional-grade antibodies
Specieshuman
AntigenIL-6
Alternative names of antigenBSF2, HGF, HSF, IFNB2
Molecular mass of antigen [kDa]21
Entrez Gene ID3569
RRIDAB_2652449, AB_2652450, AB_2652451, AB_2652452, AB_2652453, AB_2652454

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IL-6 Antibody, anti-human

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