Clone:
REA484
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
Igh-5a, Igh-5.4

Specifications for IgDa Antibody, anti-mouse, REAfinity™

Overview

Clone REA484 recognizes the mouse IgD antigen of Igh-Ca haplotype, e.g., AKR, BALB/c, CBA, C3H/He, C58, DBA/1, DBA/2, and NZB. It does not react with b and c haplotypes. IgD is expressed by peripheral mature B cells.
Additional information: Clone REA484 displays negligible binding to Fc receptors.

Alternative names

Igh-5a, Igh-5.4

Detailed product information

Technical specifications

CloneREA484
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
Antigen
IgD
a
Alternative names of antigenIgh-5a, Igh-5.4
Molecular mass of antigen [kDa]32(refers to membrane-bound form)
Distribution of antigenB cells
Entrez Gene ID380797
RRIDAB_2652293, AB_2652294, AB_2652295, AB_2652296, AB_2652297, AB_2652298, AB_2652299, AB_2652300, AB_2652301, AB_2652302, AB_2652303, AB_2652304, AB_2652305, AB_2652306

References for IgDa Antibody, anti-mouse, REAfinity™

Publications

  1. Inaoki, M. et al. (1997) CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J. Exp. Med. 186(11): 1923-1931
  2. Nitschke, L. et al. (1993) Immunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and -dependent antigens. Proc. Natl. Acad. Sci. U.S.A. 90(5): 1887-1891

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