FGF-9 stands for fibroblast growth factor 9. Human FGF-9 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Specifications for Human FGF-9

Overview

FGF-9 stands for fibroblast growth factor 9. Human FGF-9 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human FGF-9 can be used for a variety of applications, including:
  • Developmental studies of tissue differentiation.
  • Differentiation of mesenchymal cell culture.
  • Maintenance culture of neuronal and glial cells.

Detailed product information

Background information

Fibroblast growth factor 9 (FGF-9), also known as heparin-binding growth factor 9 (HBGF-9), belongs to the FGF family. FGF-9 binds several FGF receptors, FGFR 1c, 2c, 3b, 3c, and 4, and similarly to all FGF members, plays a crucial a role as cell mitogen and regulator of cell differentiation. In the nervous system, FGF-9 is secreted by neurons and induces survival signals for glial cells and astrocytes. During embryogenesis FGF-9 is a key factor for gonad development and determination of sexual phenotype, as well as skeletal development. FGF-9 is also expressed by prostatic and brain cancer.

Biological activity

  • Stimulation of thymidine uptake by BaF3 cells expressing FGF receptors
  • research grade: ≥ 2×
    10
    6
    U/mg

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Resources for Human FGF-9

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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