Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:

Specifications for HLA-A2, A28 Antibody, anti-human, REAfinity™


Clone REA142 recognizes HLA A2 and HLA A28, class I human leukocyte antigens (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of 3 domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells.
Additional information: Clone REA142 displays negligible binding to Fc receptors.

Alternative names


Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
AntigenHLA-A2, A28
Alternative names of antigenHLA-A
Molecular mass of antigen [kDa]38
Distribution of antigenB cells, dendritic cells, granulocytes, epithelial cells, lymphocytes, leukocytes
Entrez Gene ID3105
RRIDAB_2652039, AB_2652040, AB_2652041, AB_2652042, AB_2652043, AB_2652044, AB_2652045, AB_2652046, AB_2652047, AB_2652048, AB_2652049, AB_2652050, AB_2652051, AB_2652052, AB_2652053, AB_2652054, AB_2652055, AB_2652056

References for HLA-A2, A28 Antibody, anti-human, REAfinity™


  1. Hewitt, E. W. et al. (2003) The MHC class I antigen presentation pathway: strategies for viral immune evasion. Immunology 110(2): 163-169

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