Clone:
REA619
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
MHC class I, H-2D, H2-D

Specifications for H-2Db Antibody, anti-mouse, REAfinity™

Overview

Clone REA619 recognizes the mouse H-2D
b
MHC class I alloantigen expressed on mouse MHC class I
+
cells of the H-2D
b
haplotype. Reactivity to other haplotypes like, for example, a, d, f, k, n, p, q, r, s, u, and v, has not been observed.
Additional information: Clone REA619 displays negligible binding to Fc receptors.

Alternative names

MHC class I, H-2D, H2-D

Detailed product information

Technical specifications

CloneREA619
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
Antigen
H-2D
b
Alternative names of antigenMHC class I, H-2D, H2-D
Entrez Gene ID14964
RRIDAB_2651926, AB_2651927, AB_2651928, AB_2651929, AB_2651930, AB_2651931, AB_2651934, AB_2651935, AB_2651936, AB_2651937, AB_2811332

References for H-2Db Antibody, anti-mouse, REAfinity™

Publications

  1. Glithero, A. et al. (1999) Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity. Immunity 10(1): 63-74
  2. Pascolo, S. et al. (1997)
    HLA-A2.1-restricted education and cytolytic activity of CD8
    +
    T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice.
    J. Exp. Med. 185(12): 2043-2051
  3. van Stipdonk, M. J. et al. (2009) Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100. Cancer Res. 69(19): 7784-7792

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