Clone:
REA1215
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
CSF2

Specifications for GM-CSF Antibody, anti-human, REAfinity™

Overview

Clone REA1215 recognizes the human granulocyte macrophage colony-stimulating factor (GM-CSF), which is a hematopoietic growth factor that is essential for proliferation and development of granulocyte and monocyte/macrophage progenitors. It also functions as a growth factor for erythroid and megakaryocytic precursor cells in conjunction with erythropoietin. GM-CSF is secreted by various cell types including T cells, macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli and cytokines. In addition, GM-CSF strongly chemoattracts neutrophils and eosinophils and enhances the effector functions of neutrophils and macrophages.
Additional information: Clone REA1215 displays negligible binding to Fc receptors.

Alternative names

CSF2

Detailed product information

Technical specifications

CloneREA1215
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
AntigenGM-CSF
Alternative names of antigenCSF2
Molecular mass of antigen [kDa]14
Distribution of antigenT cells, endothelial cells, fibroblasts, macrophages, other
Entrez Gene ID1437
RRIDAB_2811515, AB_2811520, AB_2811516, AB_2811521, AB_2811517, AB_2811522, AB_2811518, AB_2811519

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