Clone:
REAL828
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
PIP, GCDFP15, GPIP4, prolactin induced protein, extra-parotid glycoprotein (EP-GP), gp17 seminal actin-binding protein (SABP), BRST2

Specifications for GCDFP-15 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL828 is an antibody fragment derived from the full GCDFP-15 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL828 recognizes the GCDFP-15 (gross cystic disease fluid protein 15), also known as Prolactin-inducible protein, extra-parotid glycoprotein (EP-GP), gp17 seminal actin-binding protein (SABP) or BRST2. In humans it is encoded by the PIP gene and is upregulated by prolactin and androgens and downregulated by estrogen. GCDFP-15 has various physiological functions and is used as a detection and diagnostic marker of breast cancer cells.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

PIP, GCDFP15, GPIP4, prolactin induced protein, extra-parotid glycoprotein (EP-GP), gp17 seminal actin-binding protein (SABP), BRST2

Detailed product information

Technical specifications

CloneREAL828
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenGCDFP-15
Alternative names of antigenPIP, GCDFP15, GPIP4, prolactin induced protein, extra-parotid glycoprotein (EP-GP), gp17 seminal actin-binding protein (SABP), BRST2
Distribution of antigentumor cells, breast cancer cells

References for GCDFP-15 Antibody, anti-human, REAdye_lease™

Publications

  1. Naderi, A. et al. (2012) Prolactin-induced protein mediates cell invasion and regulates integrin signaling in estrogen receptor-negative breast cancer. Breast Cancer Res. 14(4): R111
  2. Urbaniak, A. et al. (2018) Prolactin-induced protein (PIP)-characterization and role in breast cancer progression. Am. J. Cancer Res. 8(11): 2150-2164

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