Clone:
REA603
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Fz-1, Fzd1

Specifications for Frizzled-1 Antibody, anti-mouse, REAfinity™

Overview

Clone REA603 recognizes the mouse frizzled-1 antigen. Frizzled-1 is a member of the frizzled family of proteins which encode seven-transmembrane domain proteins that are receptors for the wingless-type MMTV integration site family of signaling proteins. Frizzled-1 is expressed primarily in the developing lung mesenchyme, in adult heart, placenta, kidney, pancreas, prostate, and ovary. Frizzled-1 interacts with Wnt7b.
Additional information: Clone REA603 displays negligible binding to Fc receptors.

Alternative names

Fz-1, Fzd1

Detailed product information

Technical specifications

CloneREA603
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
Cross-reactivityhuman
AntigenFrizzled-1
Alternative names of antigenFz-1, Fzd1
Molecular mass of antigen [kDa]64(same molecular weight for human and mouse/rat)
Distribution of antigenother, heart, kidney, ovary, pancreas, placenta
Entrez Gene ID8321, 14362
RRIDAB_2651784, AB_2651785, AB_2651786, AB_2651787, AB_2651788, AB_2651789, AB_2651790, AB_2651783

References for Frizzled-1 Antibody, anti-mouse, REAfinity™

Publications

  1. Sagara, N. et al. (1998) Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7. Biochem. Biophys. Res. Commun. 252(1): 117-122
  2. Gazit, A. et al. (1999) Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response. Oncogene 18(44): 5959-5966
  3. Wang, Z. et al. (2005) Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol. Cell. Biol. 25(12): 5022-5030

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