Clone:
REA663
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
FPR2, ALXR, RFP, HM63

Specifications for FPRL1/FPR2 Antibody, anti-human, REAfinity™

Overview

Clone REA663 recognizes the human FPRL1 antigen, a G-protein coupled receptor (GPCR), also known as FPR2 or N-formyl peptide receptor 2. FPRL1 mediates chemotaxis, degranulation, and the respiratory burst. It interacts with lipoxin A4, which is involved in immunomodulatory and anti-inflammatory actions. FPRL1 is expressed on mononuclear phagocytes and microglial cells.
Additional information: Clone REA663 displays negligible binding to Fc receptors.

Alternative names

FPR2, ALXR, RFP, HM63

Detailed product information

Technical specifications

CloneREA663
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenFPRL1/FPR2
Alternative names of antigenFPR2, ALXR, RFP, HM63
Molecular mass of antigen [kDa]39
Distribution of antigenmicroglia
Entrez Gene ID2358
RRIDAB_2784337, AB_2651775, AB_2651776, AB_2651777, AB_2651778, AB_2651779, AB_2651780, AB_2651781, AB_2651782, AB_2784338

References for FPRL1/FPR2 Antibody, anti-human, REAfinity™

Publications

  1. Takano, T. et al. (1997) Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J. Exp. Med. 185(9): 1693-1704
  2. Murphy, P. M. et al. (1992) A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family. J. Biol. Chem. 267(11): 7637-7643

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