Clone:
REA169
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MC, FC
Alternative names:
FPR1, FMLP, FPR

Specifications for fMLP receptor Antibody, anti-human, REAfinity™

Overview

Clone REA169 recognizes N-formyl-L-methionyl-L-leucyl-phenylalanine receptor (fMLP receptor), which is a seven transmembrane G-protein coupled receptor. fMLP receptor binds formylated peptides such as fMLP, which originate from degraded bacterial or mitochondrial proteins and mediate inflammatory reactions, activation of neutrophils and trafficking of leukocytes to the site of inflammation. Expression of fMLP receptor is mainly found on leukocytes, neutrophils and monocytes.
Additional Information: Clone REA169 displays negligible binding to Fc receptors.

Alternative names

FPR1, FMLP, FPR

Detailed product information

Technical specifications

CloneREA169
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenfMLP receptor
Alternative names of antigenFPR1, FMLP, FPR
Molecular mass of antigen [kDa]38
Distribution of antigenmacrophages, monocytes, neutrophils
Entrez Gene ID2357
RRIDAB_2651750, AB_2651751, AB_2651752, AB_2651753, AB_2651754, AB_2651755

References for fMLP receptor Antibody, anti-human, REAfinity™

Publications

  1. Paclet, M. H. et al. (2004) N-Formyl peptide receptor subtypes in human neutrophils activate L-plastin phosphorylation through different signal transduction intermediates. Biochem. J. 377: 469-477

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