Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
FCER1A, FcERI, Fce1a, Fcr-5

Specifications for FcεRIα Antibody, anti-mouse, REAfinity™


Clone REA1079 recognizes the alpha subunit of the murine high-affinity Fc receptor for IgE. The receptor is composed of one alpha, one beta, and two disulfid-linked gamma subunits, of which the alpha subunit binds IgE1. FcεRIα is expressed on mast and basophilic cells and is up-regulated in the presence of IgE. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.
Additional information: Clone REA1079 displays negligible binding to Fc receptors.

Alternative names

FCER1A, FcERI, Fce1a, Fcr-5

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenFCER1A, FcERI, Fce1a, Fcr-5
Molecular mass of antigen [kDa]26
Distribution of antigenmast cells, basophils
Entrez Gene ID14125
RRIDAB_2801720, AB_2801716, AB_2801721, AB_2801717, AB_2801722, AB_2801723, AB_2801718, AB_2801724, AB_2921731, AB_2801725, AB_2801719

Resources for FcεRIα Antibody, anti-mouse, REAfinity™


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References for FcεRIα Antibody, anti-mouse, REAfinity™


  1. Metzger, H. et al. (1989) The receptor with high affinity for IgE. Ciba Found. Symp. 147: 93-113
  2. Yamaguchi, M. et al. (2001) Regulation of mouse mast cell surface Fc epsilon RI expression by dexamethasone. Int. Immunol. 13: 843-851
  3. Kojima, T. et al. (2007)
    Mast cells and basophils are selectively activated
    in vitro
    in vivo
    through CD200R3 in an IgE-independent manner.
    J. Immunol. 179: 7093-7100

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