ExiTron V is a non-ionic, dimeric, hexaiodine-based contrast agent of low molecular weight specifically formulated for pre-clinical computed tomography (CT).
It shows strong X-ray absorption due to its covalently bound iodine atoms.
Upon intravenous injection, ExiTron V shows low plasma protein–binding and is rapidly distributed in the extracellular space.
ExiTron V is mainly excreted unchanged via glomerular filtration (kidneys).

Data and images for ExiTron V

Figures

Figure 1

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Structural formula of iodixanol.

Figure 1

Structural formula of iodixanol.

Specifications for ExiTron V

Overview

ExiTron V is a non-ionic, dimeric, hexaiodine-based contrast agent of low molecular weight specifically formulated for pre-clinical computed tomography (CT).
It shows strong X-ray absorption due to its covalently bound iodine atoms.
Upon intravenous injection, ExiTron V shows low plasma protein–binding and is rapidly distributed in the extracellular space.
ExiTron V is mainly excreted unchanged via glomerular filtration (kidneys).

Detailed product information

Applications

ExiTron V is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the vasculature.
Examples include contrast-enhanced angiography.

References for ExiTron V

Publications

  1. Heglund, I. F. et al. (1995) Preclinical pharmacokinetics and general toxicology of iodixanol. Acta Radiol. Suppl. 399: 69-82
  2. Larsen, L. E. et al. (1995) Neural tolerability of iodixanol in mice and dogs after single and repeated intracisternal administration. Acta Radiol. Suppl. 399: 238-243

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