ExiTron nano 12000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT).
It shows strong X-ray absorption due to the high metal load of the particles.
Upon intravenous injection, ExiTron nano 12000 circulates in the blood stream for a prolonged time. It accumulates in the liver and spleen due to uptake by Kupffer cells (macrophages of the liver).

Data and images for ExiTron nano 12000

Figures

Figure 1

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Schematic diagram of an ExiTron nano 12000 nanoparticle.

Figure 1

Schematic diagram of an ExiTron nano 12000 nanoparticle.

Specifications for ExiTron nano 12000

Overview

ExiTron nano 12000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT).
It shows strong X-ray absorption due to the high metal load of the particles.
Upon intravenous injection, ExiTron nano 12000 circulates in the blood stream for a prolonged time. It accumulates in the liver and spleen due to uptake by Kupffer cells (macrophages of the liver).

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Applications

ExiTron nano 12000 is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the vasculature.
Examples include contrast-enhanced angiography.

References for ExiTron nano 12000

Publications

  1. Boll, H. et al. (2010) High-speed single-breath-hold micro-computed tomography of thoracic and abdominal structures in mice using a simplified method for intubation. J. Comput. Assist. Tomogr. 34: 783-790
  2. Boll, H. et al. (2011) Micro-CT based experimental liver imaging using a nanoparticulate contrast agent: a longitudinal study in mice. PLoS One 6: e25692

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