Clone:
REA1209
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TCRA, Tcralpha

Specifications for DO11.10 TCR Antibody, anti-mouse, REAfinity™

Overview

The DO11.10 mouse model is a valuable tool for studies of T cell immigration, immunoregulation, development, activation, and function. Clone REA1209 recognizes the T cell receptor (TCR) expressed on lymphocytes of the DO11.10 transgenic mouse and the TCR of the BALB/c-derived DO11.10 and DO11.10.24 T cell hybridoma. The DO11.10 TCR is specific for the chicken ovalbumin (OVA) peptide (323-339) in the context of I-A[d] major histocompatibility (MHC) molecules. Transgenic DO11.10 T cells also recognize OVA peptide from jungle fowl and turkey in the presence of A20-1.11, the H-2d-bearing, antigen-presenting B cell lymphoma.
Additional information: Clone REA1209 displays negligible binding to Fc receptors.

Alternative names

TCRA, Tcralpha

Detailed product information

Technical specifications

CloneREA1209
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenDO11.10 TCR
Alternative names of antigenTCRA, Tcralpha
Distribution of antigenT cells
Entrez Gene ID21473
RRIDAB_2811478, AB_2811479, AB_2811480, AB_2811477

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