Clone:
REA856
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CRFB4, CRF2-4, IL-10RB, IL-10R2

Specifications for CDw210b (IL-10Rβ) Antibody, anti-mouse, REAfinity™

Overview

Clone REA856 recognizes the mouse CDw210b antigen, also known as interleukin-10 receptor beta (IL-10Rβ), a subunit of the IL-10 receptor. CDw210b is member of the type II cytokine receptor protein family and has an extracellular domain with two fibronectin type III domains. CDw210b is important for IL-10–mediated effects and is expressed on various cell types.
Additional information: Clone REA856 displays negligible binding to Fc receptors.

Alternative names

CRFB4, CRF2-4, IL-10RB, IL-10R2

Detailed product information

Technical specifications

CloneREA856
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCDw210b (IL-10Rβ)
Alternative names of antigenCRFB4, CRF2-4, IL-10RB, IL-10R2
Molecular mass of antigen [kDa]38
Distribution of antigenother
Entrez Gene ID16155
RRIDAB_2726667, AB_2726752, AB_2726668, AB_2726753, AB_2726669, AB_2726750, AB_2726666, AB_2726751

References for CDw210b (IL-10Rβ) Antibody, anti-mouse, REAfinity™

Publications

  1. Spencer, S. D. et al. (1998) The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J. Exp. Med. 187(4): 571-578
  2. Xie, M. H. et al. (2013) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275(40): 31335-31339
  3. Spach, K. M. et al. (2006) IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. J. Immunol. 177(9): 6030-6037

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