Clone:
REA222
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Cd8b1

Specifications for CD8b Antibody, anti-rat, REAfinity™

Overview

Clone REA222 recognizes rat CD8b, a member of the immunoglobulin superfamily also known as T cell surface glycoprotein Lyt-3. CD8b is expressed on cytotoxic T cells, thymocytes, and macrophages as a heterodimer with CD8a. CD8 identifies cytotoxic/suppressor T cells that interact with MHC class I bearing targets and plays a role in the process of T cell mediated killing. Flow cytometric analysis showed that CD8 T cells from lymph nodes or spleen of normal rats almost exclusively express the α/β heterodimer, regardless of the T cell receptor isotype. In contrast, natural killer cells carry only CD8a chains.
Additional information: Clone REA222 displays negligible binding to Fc receptors.

Alternative names

Cd8b1

Detailed product information

Technical specifications

CloneREA222
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesrat
AntigenCD8b
Alternative names of antigenCd8b1
Molecular mass of antigen [kDa]21
Distribution of antigengranulocytes, NK cells, T cells
Entrez Gene ID24931
RRIDAB_2659503, AB_2659504, AB_2659505, AB_2659506, AB_2659507, AB_2659508, AB_2659509, AB_2659510, AB_2659511, AB_2659512, AB_2659513, AB_2659514, AB_2659515, AB_2659516

References for CD8b Antibody, anti-rat, REAfinity™

Publications

  1. Torres-Nagel, N. et al. (1992) Differential thymus dependence of rat CD8 isoform expression. Eur. J. Immunol. 22(11): 2841-2848
  2. Duplan, V. et al. (2007)
    Tracking antigen-specific CD8
    +
    T cells in the rat using MHC class I multimers.
    J. Immunol. Methods 320(1-2): 30-39

Related products for
CD8b Antibody, anti-rat, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?