Clone:
BW135/80 Fab
Type of antibody:
Primary antibodies
Applications:
FC, MICS, IF, IHC
Alternative names:
Leu-2, Ly-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, CD8b

Specifications for CD8 Antibody, anti-human

Overview

Clone BW135/80 Fab recognizes the human CD8 antigen which is strongly expressed on human cytotoxic T cells and thymocytes, and is also expressed on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8 acts as a co-receptor for the T cell receptor and binds to the MHC class I molecule. The CD8 antibody recognizes the α-subunit of the antigen. Clone BW135/80 Fab is a clone BW135/80-derived Fab fragment of the full antibody molecule.
Additional information: Clone BW135/80 Fab displays negligible binding to Fc receptors.

Alternative names

Leu-2, Ly-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, CD8b

Detailed product information

Technical specifications

CloneBW135/80 Fab
Clonalitymonoclonal
Type of antibodyPrimary antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
AntigenCD8
Alternative names of antigenLeu-2, Ly-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, CD8b
Molecular mass of antigen [kDa]45(sum of molecular weights of subunits)
Distribution of antigendendritic cells, NK cells, red blood cells, T cells, thymocytes
Entrez Gene ID925
RRIDAB_2877035, AB_2877034

Resources for CD8 Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD8 Antibody, anti-human

Publications

  1. Jonker, M. et al. (1989) Reactivity of mAb specific for human CD markers with rhesus monkey leucocytes. Oxford, Oxford University Press (Leukocyte Typing IV): 1058-1063

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